Indian stock markets declined sharply during the opening session on Tuesday following the strong sell-off in U.S. markets, reacting to the "Trump Uncertainty Discount" that is affecting global supply chains. The Nifty 50 index opened at 22,345.95 with a decline of 114.35 points or -0.51 per cent, while the BSE Sensex lost 371.29 points or -0.50 per cent to open at 73,743.88.