Sevilla ousted AS Roma 2-0 in the previous round. Sergio Reguilon opened the scoring for the Spanish side before Youssef En-Nesyri doubled the lead. Sevilla went 2-0 up in the first half and Roma’s fightback was dented with a red card to Gianluca Mancini. Wolves beat Olympiacos in the last 16 thanks to a Raul Jimenez penalty in the eighth minute.