Business News | CliniExperts Conducts Successful Study, Affirming ALFLUTOP®'s Benefits for Indian Osteoarthritis Patients
Get latest articles and stories on Business at LatestLY. New Delhi [India], January 28: CliniExperts, one of India's premier Clinical Research Organizations, successfully conducted a phase III study on its biotherapeutic product, ALFLUTOP®, to assess the efficacy, safety, and tolerability in Indian patients with knee osteoarthritis. Such a scientific study proved ALFLUTOP® not just efficacious but could help in drastically improving the quality of life of patients in India, where osteoarthritis increasingly becomes a huge public health problem.
SMPL
New Delhi [India], January 28: CliniExperts, one of India's premier Clinical Research Organizations, successfully conducted a phase III study on its biotherapeutic product, ALFLUTOP®, to assess the efficacy, safety, and tolerability in Indian patients with knee osteoarthritis. Such a scientific study proved ALFLUTOP® not just efficacious but could help in drastically improving the quality of life of patients in India, where osteoarthritis increasingly becomes a huge public health problem.
The study sought to fill a significant void in the current literature concerning the efficacy of ALFLUTOP® within the Indian demographic. Although the product has been available in the market for 27 years, showcasing a reliable and stable safety profile, the particular effects and safety of ALFLUTOP® in Indian patients had not been comprehensively investigated prior to this study. CliniExperts established a robust study design that involved 218 evaluable subjects, aged 40 to 75 years, who were randomly assigned to receive either ALFLUTOP® or standard care treatment over a duration of 56 days.
The clinical trial was structured as a prospective, randomized, double-blind, multicentric phase III study carried out at seven locations throughout India. Participants were administered either ALFLUTOP®, a natural chondroprotective product known for its anti-inflammatory properties, or standard care treatment over a duration of 20 days. The study comprised four distinct visits, facilitating comprehensive monitoring and assessment of the outcomes.
Also Read | Kareena Kapoor Khan, Sara Ali Khan’s Black Lehengas for Your Next Reception Party Wardrobe (View Pics).
The primary endpoints were the percent change in WOMAC scores, a standardized process for assessing the impact of osteoarthritis on a patient's quality of life. Findings were striking out of 218 evaluable subjects, patients in the ALFLUTOP® group demonstrated a reduction in WOMAC pain score at week 4 by 29.4% in comparison with only 11.9% in the standard care group. By Week 8, the relative reduction of pain scores for ALFLUTOP® appeared to have increased to 45.7%, significantly outpacing that seen in the standard care group by 33.2%. The difference was statistically significant with a p-value
(The above story is verified and authored by ANI staff, ANI is South Asia's leading multimedia news agency with over 100 bureaus in India, South Asia and across the globe. ANI brings the latest news on Politics and Current Affairs in India & around the World, Sports, Health, Fitness, Entertainment, & News. The views appearing in the above post do not reflect the opinions of LatestLY)